We Can, Must, and Will Simulate Nematode Brains

We Can, Must, and Will Simulate Nematode Brains

4/1/2025

notes

i appreciate the historical walk through and the tighter definitions of what is being proposed.

technical, the challenge ahead is appreciable and exciting.

what is less clear are alternative ways to achieve similar research outcomes (which is also left mostly to the reader)

i believe in the power of models and simulations. but the costs of doing that for the brain are high and it would be nice to know what are the first 10 things we would do.

link

https://asteriskmag.com/issues/09/we-can-must-and-will-simulate-nematode-brains

summary

Scientists have been trying to simulate the C. elegans brain for over 25 years. Recent advances in microscopy and machine learning have made it possible to collect and analyze data needed for a more realistic simulation. The author discusses the challenges and progress made, along with the potential implications of successfully simulating a nematode brain, and how this would help to pave the way for the simulation of more complex organisms like humans.

tags

nematode ꞏ brain simulation ꞏ C. elegans ꞏ connectome ꞏ microscopy ꞏ machine learning ꞏ neuroscience