The Risk of Cancer Fades as We Get Older, And We May Finally Know Why
The Risk of Cancer Fades as We Get Older, And We May Finally Know Why
Aging brings two opposing trends in cancer risk: first, the risk climbs in our 60s and 70s, as decades of genetic mutations build up in our bodies. But then, past the age of around 80, the risk drops again – and a new study may explain a key reason why. A protein called NUPR1 appears to limit iron availability in aging stem cells, restricting both healthy regeneration and the growth of cancerous tumors.
Note
it feels not too surprising that as we age, our cells don't grow as much.
but the path way in which this happens is a fascinating find. this article talks about using this knowledge to better understand and possible delay cancer.
I wonder if their are implications to longevity research as well.
Link
Published
2024
Summary
Aging brings two opposing trends in cancer risk: first, the risk climbs in our 60s and 70s, as decades of genetic mutations build up in our bodies. But then, past the age of around 80, the risk drops again – and a new study may explain a key reason why. A protein called NUPR1 appears to limit iron availability in aging stem cells, restricting both healthy regeneration and the growth of cancerous tumors.
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