The Quest to Cure Progeria Is a Quest to Slow Aging

https://www.newyorker.com/magazine/2025/08/18/how-an-ultra-rare-disease-accelerates-aging
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The Quest to Cure Progeria Is a Quest to Slow Aging

This article from The New Yorker explores the rare genetic disorder progeria, which causes rapid aging, and the ongoing scientific efforts to find a cure. It delves into the personal stories of individuals with progeria, such as Sam Berns and Kaylee Halko, and highlights the groundbreaking research led by figures like Leslie Gordon, Francis Collins, and David R. Liu in gene editing and CRISPR technology. The narrative covers the challenges faced by patients and researchers, the development of potential treatments like lonafarnib and the gene-editing therapy SamPro-1, and discusses the broader implications of this research for understanding and potentially slowing the general human aging process.

Note

if the scientist say it will take one year, then it will take at least three.

if only life could move as slowly as project estimates...

Published

2025

Summary

This article from The New Yorker explores the rare genetic disorder progeria, which causes rapid aging, and the ongoing scientific efforts to find a cure. It delves into the personal stories of individuals with progeria, such as Sam Berns and Kaylee Halko, and highlights the groundbreaking research led by figures like Leslie Gordon, Francis Collins, and David R. Liu in gene editing and CRISPR technology. The narrative covers the challenges faced by patients and researchers, the development of potential treatments like lonafarnib and the gene-editing therapy SamPro-1, and discusses the broader implications of this research for understanding and potentially slowing the general human aging process.

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