A primer on the current state of longevity research

A primer on the current state of longevity research

5/9/2025

notes

I love the idea of primers as a way to disseminate hard to understand and follow research.

it tackles a lot of the problems introduced by overzealous marketing departments of universities and research labs: hype and a lack of simmering time.

unfortunately, most primers likely will end as this does: too many unknowns and so much more research to do.

it's not a bad outcome but disheartening in a world of massive NIH contraction

link

https://www.owlposting.com/p/some-questions-and-answers-i-had

summary

This article is a primer on the current state of longevity research. It discusses the therapeutic focus on sirtuins, longevity-focused research institutions/grant programs/startups, cellular reprogramming, and biological clocks.

tags

longevity ꞏ sirtuins ꞏ cellular reprogramming ꞏ biological clocks ꞏ aging research ꞏ NAD+ ꞏ NMN ꞏ NR ꞏ resveratrol ꞏ fisetin ꞏ quercetin ꞏ epigenetic clocks ꞏ telomere length ꞏ transcriptomics ꞏ proteomics